Dietary sodium manipulation during critical periods in development sensitize adult offspring to amphetamines
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Dietary sodium manipulation during critical periods in development sensitize adult offspring to amphetamines.
This study examined critical periods in development to determine when offspring were most susceptible to dietary sodium manipulation leading to amphetamine sensitization. Wistar dams (n = 6-8/group) were fed chow containing low (0.12% NaCl; LN), normal (1% NaCl; NN), or high sodium (4% NaCl; HN) during the prenatal or early postnatal period (birth to 5 wk). Offspring were fed normal chow therea...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
سال: 2008
ISSN: 0363-6119,1522-1490
DOI: 10.1152/ajpregu.00186.2008